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Abstract #3749

Evaluation of a flexible polyimide-based microelectrode array for MR-compatibility and recording performance in 7T research system

Xiao Yu1,2, Bo-Wei Chen3, Boyi Qu1,4, Tingting He1, You-Yin Chen3, and Hsin-Yi Lai1,5

1Interdisciplinary Institute of Neuroscience and Technology, Qiushi Academy for Advanced Studies, Zhejiang University, Hangzhou, China, 2Department of Neurobiology, Zhejiang University School of Medicine, Hangzhou, China, 3Department of Biomedical Engineering, National Yang Ming University, Taiwan, China, 4College of Biomedical Engineering & Instrument Science，Zhejiang University, Hangzhou, China, 5The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China

For simultaneous recording of spike signal and functional magnetic resonance imaging (fMRI) response, both MR-compatibility and performance of electrophysiological signal acquisition of the electrode matters. Previously, we have designed a flexible polyimide-based microelectrode array which has good biocompatibility, as well as high and stable signal-to-noise ratio for chronic recording. This study evaluated the MR-compatibility and recording performance of microelectrode array in the 7T research system (Siemens, Erlangen, Germany). The results suggest that it has the potential to facilitate simultaneous spike-recording during MR scanning in 7T.

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