In this study, we employed diffusion kurtosis imaging (DKI) to test for differences in gray matter (GM) microstructure in schizophrenia (SZ) and autism spectrum disorder (ASD). Significantly increased metrics of DKI were found in SZ compared to HC participants, while significantly decreased metrics of DKI were found in ASD compared to HC in the temporal lobe and sub-lobar temporal regions of interest (ROIs). In vivo DKI metrics appear to be sensitive to GM microstructural pathology in SZ and ASD and may provide new information on the neural underpinnings of these disorders.
This abstract and the presentation materials are available to members only; a login is required.