Abstract #3511

A Multi-Echo Stejskal-Tanner EPI Sequence for Rapid Measurements of T2 and Diffusion Tensor Correlations

Richard Buschbeck¹, Ezequiel Farrher¹, Kuan-Hung Cho², Ming-Jye Chen², Seong Dae Yun¹, Chang-Hoon Choi¹, Li-Wei Kuo^2,3, and N. Jon Shah^1,4,5,6

¹Institute of Neuroscience and Medicine 4, Jülich Research Centre, Jülich, Germany, ²Institute of Biomedical Engineering and Nanomedicine, National Health Research Institutes, Miaoli, Taiwan, ³Institute of Medical Device and Imaging, National Taiwan University College of Medicine, Taipei, Taiwan, ⁴Department of Neurology, RWTH Aachen University, Aachen, Germany, ⁵Institute of Neuroscience and Medicine 11, Jülich Research Centre, Jülich, Germany, ⁶JARA - BRAIN - Translational Medicine, Aachen, Germany

Initial phantom and in vivo results of a multi-echo Stejskal-Tanner EPI sequence are presented demonstrating the feasibility of rapid measurements for diffusion tensor and T₂ correlations. The diffusion and T₂ maps are artefact-free and are found to be very similar to the ones derived from the conventional individual-echo methods. However, the data tend to display slightly overestimated diffusivities and T₂, which need to be investigated further.

Compared to the standard method, the proposed multi-echo sequence reduces the scan time by a factor of five, which is necessary to make multidimensional diffusion techniques feasible in clinical settings.

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