Abstract #3498

Using symmetrized temporal gradient profiles for water diffusion pore imaging on a 14.1 T spectrometer

Dominik Ludwig^1,2, Frederik Bernd Laun³, Karel D. Klika⁴, Peter Bachert¹, and Tristan Anselm Kuder¹

¹Department of Medical Physics in Radiology, German Cancer Research Center (DKFZ), Heidelberg, Germany, ²Faculty of Physics and Astronomy, Heidelberg University, Heidelberg, Germany, ³Institute of Radiology, University Hospital Erlangen (FAU), Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany, ⁴Molecular Structure Analysis, German Cancer Research Center (DKFZ), Heidelberg, Germany

Diffusion pore imaging can be used to retrieve the pore-space function of an arbitrary closed pore. While a few publications involving pore imaging using the long–narrow gradient approach exist [1–3], all of them involve the use of sophisticated acquisition schemes like CPMG or involve an additional readout gradient. In this study, we were able to show that it is indeed possible to acquire the pore space function of capillaries with a diameter of 15 µm using a simple modification of the long–narrow gradient scheme on a 14.1 T NMR spectrometer.

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