Abstract #3489

Silent Distortionless DWI

Jianmin Yuan¹, Yuxin Hu^1,2, Anne Menini³, Christopher M. Sandino², Jesse Sandberg⁴, Marcus Alley¹, Michael Lustig⁵, Brian Hargreaves¹, and Shreyas Vasanawala¹

¹Radiology, Stanford University, Stanford, CA, United States, ²Electrical Engineering, Stanford University, Stanford, CA, United States, ³GE Healthcare, Menlo Park, CA, United States, ⁴Pediatric Radiology, Lucile Packard Children’s Hospital, Stanford University, Stanford, CA, United States, ⁵Electrical Engineering and Computer Science, UC Berkeley, Berkeley, CA, United States

Standard clinical EPI based diffusion sequence has high acoustic noise, which is uncomfortable for patients. The images acquired by single-shot EPI also suffer from distortion in areas of large susceptibility variations. To overcome these two limitations, we have developed a silent and distortion-free DWI sequence using a driven equilibrium diffusion prepared multi-segmented Rotating Ultra-Fast Imaging Sequence (RUFIS) readout. The sequence was validated in phantom, volunteers, and patients. The results showed the proposed sequence provides similar diffusion contrast and ADC measurement compared to DW-EPI, with improved image quality and a sound level that approaches that of ambient noise.

This abstract and the presentation materials are available to members only; a login is required.

Join Here