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Abstract #3273

Altered Connectivity Using Resting State fMRI in SCA1 and SCA2 Patients

Dibashree Tamuli1, Shefali Chaudhary2, S. Senthil Kumaran2, Ashok Kumar Jaryal1, Achal Kumar Srivastava3, and Kishore Kumar Deepak1

1Physiology, All India Institute of Medical Sciences, New Delhi, New Delhi, India, 2NMR, All India Institute of Medical Sciences, New Delhi, New Delhi, India, 3Neurology, All India Institute of Medical Sciences, New Delhi, New Delhi, India

Neurodegeneration in cortical and subcortical brain areas are found in SCA type 1 and 2 patients. The structural brain volumetric analysis has been done to know the differential loss of volume of brain areas in SCA type 1 and 2. Especially, to find the functional connectivity of the whole brain in the same SCA patients, we have assessed default mode network using resting state fMRI.

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