The current study used anatomic magnetic resonance (MR) imaging to evaluate cortical structure alterations, age-related cortical and structural co-variance differences between children with intermittent exotropia (IXT) and healthy controls. The morphologic changes in the visual cortex and associations cortices, different anatomical-age correlation, and abnormal structural co-variance were detected in IXT group. These findings suggest possible disruptions of the cortical visual networks and the cortical maturation in IXT.
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