Quantitative susceptibility mapping (QSM) has been increasingly used to help access the brain development, especially white matter myelination. However, the quantitative accuracy is limited by its angle dependence to the magnetic field. In this study, ultrahigh resolution diffusion tensor imaging (DTI) was used to delineate the fiber bundles (i.e. corpus callosal fibers), followed by tract-based QSM to minimize the angle dependence and accurately assess magnetic susceptibility changes in different brain regions.
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