Abstract #2646

A high-resolution MRI template for adult Beagle dog

Xueru Liu^1,2, Rui Tian^2,3,4, Zhentao Zuo^1,2,4, Hui Zhao^3,5, Liang Wu^2,3, Yan Zhuo^1,2,4, Yongqing Zhang^2,3,4, and Lin Chen^1,2,4

¹State Key Laboratory of Brain and Cognitive Science, Institute of Biophysics,Chinese Academy of Sciences, Beijing, China, ²University of Chinese Academy of Sciences, Beijing, China, ³State Key Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, China, ⁴CAS Center for Excellence in Brain Science and Intelligence Technology, Chinese Academy of Sciences, Beijing, China, ⁵Key Laboratory of Regenerative Biology, South China Institute for Stem Cell, Biology and Regenerative Medicine, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China

High-resolution T1w and T2w templates from 10 male adult purebred beagles were created in this study. According to the tissue probability map, descriptive statistics of brain tissue volumes and brain sizes exhibit our template with smaller variance. Significant correlation between brain size from dorsal to ventral and gray matter volume was found. This high-resolution purebred canine brain template lays the foundation for further studies aimed at in-vivo analysis of the development of canine brain anatomy and function.

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