Abstract #2599

Investigation of brain plasticity during prolonged Braille learning in sighted subjects: a longitudinal diffusion MRI (dMRI) study

Malwina Molendowska¹, Bartosz Kossowski¹, Jacek Matuszewski¹, Łukasz Bola^1,2, Marcin Szwed², Katarzyna Jednoróg³, and Artur Marchewka¹

¹Laboratory of Brain Imaging, Neurobiology Center, Nencki Institute of Experimental Biology, Polish Academy of Sciences, Warsaw, Poland, ²Department of Psychology, Jagiellonian University, Cracow, Poland, ³Laboratory of Psychophysiology, Nencki Institute of Experimental Biology, Polish Academy of Sciences, Warsaw, Poland

Diffusion MRI can be used to evaluate the brain plasticity processes that occur during new skills acquisition. Commonly, one of the tasks used to investigate neuroplasticity of both blind and sighted subjects is Braille reading. In this work, we analyze DTI metrics based on 5 time points data and investigate the dynamics of the brain reorganization processes. In particular, our preliminary results depict neuronal brain changes within main WM tracts associated with somatosensory area development.

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