Interpretation of diffusion and perfusion MRI in the hyper-FLAIR is challenging. In this work, biopsies were extracted from 16 subjects and infiltrative tumorous stem cells were counted and cultivated intraoperatively to measure their aggressiveness. Diffusion was found to be a good predictor of the time to form tumorous neurospheres. Glioblastoma stem cells were found preferably in regions with strong perfusion, that is to say near vascular niches.
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