Abstract #2197

DANTE-Prepared FLASH: Three-Dimensional Vessel Wall Imaging Of ApoE-/- Mouse at 7 Tesla

Yuanbo Yang¹, Zhonghao Li², Yingjie Mei³, Ming Zhao², Guoxi Xie⁴, and Yanqiu Feng¹

¹School of Biomedical Engineering, Guangdong Provincial Key Laborary of Medical Image Processing, Southern Medical University, Guangzhou, People's Republic of China, Guangzhou, China, ²Department of Pathophysiology, Key Lab for Shock and Microcirculation Research of Guangdong, Southern Medical University, Guangzhou, 510515, PR China, Guangzhou, China, ³Philips Healthcare， Guangzhou， China, Guangzhou, China, ⁴Department of Biomedical Engineering, School of Basic Sciences, Guangzhou Medical University, Guangzhou, China

There is a growing preclinical demand for methods to characterize atherosclerotic plaque in vivo. Recently proposed DANTE for dark-blood preparation successfully in vessel wall imaging. However, previous studies were performed at 3T and used for vessel wall imaging of human. It remains unclear that if DANTE module could be used for apoE-/- mouse at 7T. Here we demonstrated a sequence using DANTE dark-blood preparation combined with FLASH readout (DANTE-FLASH) for three-dimensional (3D) vessel wall imaging at 7 Tesla (T).

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