Myocardial perfusion imaging is a valuable diagnostic tool to assess cardiac viability. Quantitative perfusion imaging promises to provide absolute values of myocardial perfusion allowing for objective disease assessment and monitoring. Here we present a phantom study evaluating accuracy and reproducibility of a high-resolution dynamic T1 mapping approach to directly measure changes in contrast agent concentration and yield quantitative myocardial perfusion without the need of signal-intensity calibration. Our proposed technique provides one high-resolution T1 map for each cardiac cycle and leads to accurate myocardial perfusion values verified with standard 2D phase-contrast MRI (difference of estimated flow 10 – 20%).
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