Abstract #1923

Whole Body Quadrature Birdcage RF Coil for 23Na MRI of Small Rodents at 9.4T and Its Application in Sodium Imaging of the Eye and Kidneys

Laura Boehmert¹, Helmar Waiczies², Daniel Wenz¹, Celal Oezerdem¹, Andre Kuehne², Paula Ramos Delgado³, Erdmann Seeliger⁴, Andreas Pohlmann¹, and Thoralf Niendorf^1,2

¹Berlin Ultrahigh Field Facility (B.U.F.F.), Max Delbrück Center for Molecular Medicine in the Helmholtz Association, Berlin, Germany, ²MRI.TOOLS GmbH, Berlin, Germany, ³Berlin Ultrahigh Field Facility (B.U.F.F.), Max Delbrück Center for Molecular Medicine in the Helmholtz, Berlin, Germany, ⁴Institute of Vegetative Physiology, Charité - University Medicine Berlin, Berlin, Germany

Sodium ions play a major role in the physiology of the human organism. The kidneys and eyes both have a high sodium concentration, and we suggest that probing tissue sodium concentration in these organs using ²³Na MRI can add a very useful dimension to our understanding of renal and ocular disorders. Changes in the sodium concentration might be indicative of early pathophysiological changes in such diseases. Therefore we present a quadrature birdcage coil tailored for sodium imaging of small rodents at 9.4T, along with the RF coil design, EMF simulations and in vivo ²³Na MRI of the eye and kidney.

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