Abstract #1921

The Effect of Water Loading on Renal Diffusion Parameters with Triexponential Analysis

Yuki Koshino¹, Naoki Ohno², Tosiaki Miyati², Kotaro Yoshida³, Satoshi Kobayashi^1,2,3, Naoki Hori¹, Yukihiro Matsuura¹, and Toshifumi Gabata³

¹Department of Radiological Technology, Kanazawa University Hospital, Kanazawa, Japan, ²Faculty of Health Sciences, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, Kanazawa, Japan, ³Department of Radiology, Kanazawa University Hospital, Kanazawa, Japan

To assess the response of water loading on diffusion parameters in the renal tissue, we evaluated renal diffusion coefficients with tri- and biexponential analyses before and after water loading. Our results showed that slow-restricted diffusion coefficient with triexponential analysis in the renal medulla was significantly increased after water loading, whereas none of the diffusion parameters with biexponential analysis significantly changed. Diffusion analysis with triexponential function could enable us to obtain more detailed information on renal function.

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