Atheroembolic renal disease (AERD) is part of a multisystemic disease caused by showers of cholesterol emboli from the atherosclerotic aorta to many organs and is usually associated with poor renal and patient survival. The specific evolution of renal tissue properties remains unclear because of the lack of sensitive imaging biomarkers to detect subtle AERD lesions. Once the embolus enters the blood circulation, it will cause tissue ischemia, endothelial inflammation and even renal function damage. Therefore, the level of blood oxygen is a perfect pointcut for AERD development. In this study, we aim to use blood oxygenation level dependent (BOLD) MRI to evaluate longitudinal changes in kidney properties before and after AERD appearance.
This abstract and the presentation materials are available to members only; a login is required.