Abstract #1833

MRI-Derived Patient Specific Molds for Cancer Lesion Analysis in the Prostate

David R Rutkowski^1,2, Shane A Wells², Brian Johnson³, Wei Huang⁴, David F Jarrard⁵, Joshua M Lang⁶, Steve Cho², and Alejandro Roldán-Alzate ^1,2

¹Mechanical Engineering, University of Wisconsin-Madison, Madison, WI, United States, ²Radiology, University of Wisconsin-Madison, Madison, WI, United States, ³Biomedical Engineering, University of Wisconsin-Madison, Madison, WI, United States, ⁴Pathology, University of Wisconsin-Madison, Madison, WI, United States, ⁵Urology, University of Wisconsin-Madison, Madison, WI, United States, ⁶Medicine, University of Wisconsin-Madison, Madison, WI, United States

Magnetic Resonance Imaging (MRI), and emerging Prostate Specific Membrane Antigen (PSMA) Positron Emission Tomography (PET)/MRI, can be used to detect and locate prostate cancer. The accuracy of this method can be validated by comparing post-prostatectomy histopathology information to MRI and PET image data with the help of a custom prostate-sectioning device. This study is aimed at addressing sectioning device limitations proposed by previous studies and at developing a three-dimensional (3D) comparison method for MRI data and post-prostatectomy prostate geometries.

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