Despite its strong clinical significance in lesion detection and tumor staging, liver DWI remains challenged by its strong sensitivity to motion effects. Motion-compensated diffusion encoding schemes have recently been proposed to improve DW liver signal homogeneity especially in the left liver lobe, a region typically affected by cardiac motion. However, motion-compensated diffusion encoding is associated with hyperintense vessel signal even at high b-values, which can obscure lesion detection. The present work proposes a partial velocity-compensated diffusion encoding using asymmetric diffusion gradients for combined motion compensation and residual vessel signal suppression in liver DWI, optimized for short echo times.
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