Abstract #1698

Comparison of MR elastography and intravoxel incoherent motion for the prediction of hepatocellular carcinoma tumor capsule formation in hepatitis B virus-related patients using whole-tumor analysis

Yao Zhang¹, Qungang Shan¹, Sichi Kuang¹, Bingjun He¹, Jingbiao Chen¹, Bing Wu², Tianhui Zhang¹, Ying Deng¹, Kevin J Glaser³, Sudhakar K Venkatesh³, Richard L Ehman³, and Jin Wang¹

¹Department of Radiology, The third affiliated hospital of Sun Yat-sen University, Guangzhou, China, ²MR Research China, GE Healthcare, Beijing, China, ³Department of Radiology, Mayo Clinic, Rochester, MN, United States

Hepatocellular carcinoma (HCC) is the most common primary malignant hepatic tumor worldwide and the prognosis remains poor. Tumor capsule formation is a favorable factor for predicting invasiveness and prognosis. We explored the potential value of MR elastography（MRE）and intravoxel incoherent motion（IVIM）for the prediction of tumor capsule formation in patients with hepatitis B virus-related (HBV) HCCs using whole-tumor analysis. Results showed that mean tumor stiffness may be useful for the prediction of capsule formation of HCCs. The utility of the mean value of IVIM metrics may need to be further explored.

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