Abstract #1689

Radiomics analysis of gadoxetic acid-enhanced MRI for the evaluation of HCC treatment response to Yttrium-90 radioembolization

Stefanie Hectors^1,2, Amy Law^1,2, Edward Kiim², Sara Lewis^1,2, and Bachir Taouli^1,2

¹Translational and Molecular Imaging Institute, Icahn School of Medicine at Mount Sinai, New York, NY, United States, ²Department of Radiology, Icahn School of Medicine at Mount Sinai, New York, NY, United States

The goal of our study was to assess the predictive value of radiomics features assessed on pre-treatment multi-phasic gadoxetic acid-enhanced (EOB-)MRI for prediction of response of hepatocellular carcinoma to ⁹⁰Yttrium radioembolization (RE). We found that radiomics features measured at baseline were predictive of response assessed at 6 weeks and 6-12 months after treatment. These results indicate value of radiomics for prediction of RE response, which needs to be validated in a larger study.

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