Abstract #1671

Quantitative dynamic contrast-enhanced magnetic resonance imaging as a potential tool for preoperative predicting the response to neoadjuvant chemotherapy in locally advanced gastric adenocarcinoma

Yongjian Zhu¹, Ying Li¹, Jun Jiang¹, Wen Zhang², Liming Jiang¹, and Lizhi Xie³

¹Department of Imaging Diagnosis, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China, ²Department of Medical Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China, ³GE healthcare, China, Beijing, China

Dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) has been applied in diagnosis of different cancers, however its potential in gastric cancer has not been fully explored. In this study, we research into the value of DCE-MRI parameters in evaluating the response to chemotherapy in gastric cancer. It was found that the Ktrans and Ve values showed good predictive performance through distinguishing responders from non-responders, which could provide effective technical assistance for the choice of clinical treatment.

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