Abstract #1595

A 3T MRI platform for imaging rodent models by integrating a dedicated high-strength gradient coil on a whole-body magnet

Sheng-Min Huang^1,2, Kuan-Hung Cho¹, Ming-Jye Chen¹, Hsuan-Han Chiang¹, Chang-Hoon Choi³, Richard Buschbeck³, Ezequiel Farrher³, N. Jon Shah^3,4,5,6, Ruslan Garipov⁷, Ching-Ping Chang⁸, Hsu Chang¹, and Li-Wei Kuo^1,9

¹Institute of Biomedical Engineering and Nanomedicine, National Health Research Institutes, Miaoli, Taiwan, ²Department of Biomedical Engineering and Environmental Sciences, National Tsing Hua University, Hsinchu, Taiwan, ³Institute of Neuroscience and Medicine 4, INM-4, Forschungszentrum Jülich, Jülich, Germany, ⁴Institute of Neuroscience and Medicine 11, INM-11, JARA, Forschungszentrum Jülich, Jülich, Germany, ⁵JARA - BRAIN - Translational Medicine, Aachen, Germany, ⁶Department of Neurology, RWTH Aachen University, Aachen, Germany, ⁷MR Solutions Ltd., Guildford, United Kingdom, ⁸Department of Medical Research, Chi Mei Medical Center, Tainan, Taiwan, ⁹Institute of Medical Device and Imaging, National Taiwan University College of Medicine, Taipei, Taiwan

In this study, a high-strength gradient coil dedicated for imaging rodent models has been successfully integrated on a whole-body 3T MRI magnet. The imaging capability of this system has been qualitatively and quantitatively demonstrated using phantom, ex-vivo specimen and in-vivo rat experiments. Since the hardware components used for integration on our system are independent from system vendors, this study can be a practically useful guide, especially for those who want to conduct small animal imaging on clinically used magnets.

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