Due to sensitivity and invasiveness issues, the use of implanted NMR microprobes remains a poorly explored field of research, with no emerging or significant biomedical applications. In this study, we report the realization, characterization and applicaiton of an innovative design for implantable microprobe allowing a drastic minimization of the probe invasiveness. The results obtained in vitro and in vivo demonstrate the potential of this microprobe architecture for MRS and MRI investigation of organs and tissues in submicroliter volumes.
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