This study presents the analysis of 78 total hip arthroplasty revision subjects that underwent advanced MRI off-resonance analysis and optical histology necrosis grading of tissue biopsies. The off-resonance analysis, which leverages multi-spectral MRI methods, sought to quantify metal particle deposition in tissues or “metallosis”. Direct measurements of off-resonance signatures correlated strongly with histology necrosis grade (p < 0.013). The results of this study provide encouragement that quantitative MRI may be useful as a non-invasive biomarker of tissue destruction in symptomatic total hip arthroplasty.
This abstract and the presentation materials are available to members only; a login is required.