Usefulness of 3-dimensional MR Texture Analysis (3D-MRTA) for Distinguishing Well-differentiated Liposarcoma fom Lipoma

Although magnetic resonance (MR) imaging has been used as standard imaging tool, because of overlapping imaging features, the discrimination between well-differentiated liposarcoma and lipoma is not always clear. Also, no study has evaluated the diagnostic usefulness of 3-dimensional MR texture analysis (3D-MRTA) for distinguishing well-differentiated liposarcoma from lipoma. Therefore, the purpose of this study is to evaluate the usefulness of 3D-MRTA for differentiation between well-differentiated liposarcoma and lipoma, diagnosed on the basis of histopathological features. Regarding mean, MPP, kurtosis, and entropy, values on all sequences were significantly higher in well-differentiated liposarcoma than those in lipoma (p<0.001). The two best performing 3D-MRTA parameters were kurtosis on T2WI (AUC, 0.86; 95 % CI, 0.77-0.95) and entropy on FS-T1CE (AUC, 0.83; 95 % CI, 0.74- 0.93). There were good or excellent interobserver agreements for all measurements (ICC, 0.750–0.885).