Abstract #1333

Short-Term Effects of Running on T2 Relaxation Times of Femoral Cartilage in Female Runners

Hollis A Crowder¹, Valentina Mazzoli², Marianne Black¹, Lauren Watkins³, Feliks Kogan², Brian Hargreaves^2,4, Marc Levenston^1,3, and Garry Gold^2,3

¹Mechanical Engineering, Stanford University, Palo Alto, CA, United States, ²Radiology, Stanford University, Palo Alto, CA, United States, ³Bioengineering, Stanford University, Palo Alto, CA, United States, ⁴Electrical Engineering, Stanford University, Palo Alto, CA, United States

This study tracks changes in water content in femoral cartilage from running by comparing T₂ relaxation times of cartilage at baseline, time 0, and time 60 minutes post-run. Significant decreases in T₂ relaxation times between baseline and time 0/time 60 minutes post-run scans occurred in superficial and deep cartilage, and a significant increase in T₂ relaxation time occurred between time 0 and time 60 minutes post-run scans in deep cartilage, suggesting a reduction and partial recovery of cartilage water content. This study demonstrates the high sensitivity of T₂ to cartilage loading patterns during running and supports the potential of using this setup as a method for identifying early changes in cartilage health.

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