Abstract #1299

Optimal flip angle for imaging and T2* mapping of the human skull using ultra-short echo-time (UTE) imaging

Martin Krämer¹, Benedikt Herzau¹, and Jürgen R Reichenbach^1,2,3,4

¹Medical Physics Group, Institute of Diagnostic and Interventional Radiology, Jena University Hospital - Friedrich Schiller University Jena, Jena, Germany, ²Michael Stifel Center for Data-driven and Simulation Science Jena, Friedrich Schiller University Jena, Jena, Germany, ³Abbe School of Photonics, Friedrich Schiller University Jena, Jena, Germany, ⁴Center of Medical Optics and Photonics, Friedrich Schiller University Jena, Jena, Germany

To investigate the influence of the flip angle on imaging and T₂^* mapping of the human skull, multi-echo 3D ultra-short echo-time (UTE) imaging was performed for multiple flip angles ranging from 5° to 49°. Results based on difference images between two echoes indicate that higher flip angles are better suited for separating the skull from adjacent tissues. In addition, a strong dependency of the skulls T₂^* values on the flip angle was observed

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