The aim of this study was to quantitatively describe the relation between fat calibration in ME-SE water T2 mapping and STEAM fat T2 relaxation measurements in spectroscopy using j‑coupling simulations and investigate its effect on EPG water T2 mapping. Both ME-SE and STEAM T2 mapping methods to estimate the apparent fat T2 relaxation times are heavily influenced by J-coupling. As such the measured T2 relaxation time of fat using STEAM, appears shorter and using ME-SE appears longer, ranging between values of 30 and 140 ms.
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