Prostate cancer (PCa) is the second leading cause of cancer deaths among males in the in the United States. Early detection of clinically significant PCa is a major challenge. MR elastography (MRE) is a noninvasive technique capable of quantifying the mechanical properties of tissue and has shown promising results in the detection and localization of PCa. Our results show that transpelvic three-dimensional (3D) MRE using a pelvic wall driver could be successful performed in the prostate at the frequencies of 60 Hz and 90 Hz and can provide a potential quantitative biomarker to evaluate prostate diseases.
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