Abstract #0969

A Variable Flip Angle Golden-Angle-Ordered 3D Stack-of-Radial Sequence for Combined PRF/T1 Monitoring of MR-Guided HIFU Ablation

Le Zhang¹, Tess Armstrong^1,2, Xinzhou Li^1,3, and Holden H. Wu^1,2,3

¹Radiological Sciences, University of California, Los Angeles, Los Angeles, CA, United States, ²Physics and Biology in Medicine Interdepartmental Program, University of California, Los Angeles, Los Angeles, CA, United States, ³Department of Bioengineering, University of California, Los Angeles, Los Angeles, CA, United States

Proton resonance frequency (PRF) shift is widely used for MR temperature mapping, but fails in adipose tissues. T₁ measurement offers an alternative temperature mapping method in adipose tissues. Combined PRF-T₁ temperature mapping has been evaluated for Cartesian MRI, but there is a lack of research for non-Cartesian techniques. In this work, we propose a new 3D stack-of-radial technique for combined PRF-T₁ MR temperature mapping. Results from non-heating in vivo scans demonstrate good stability of T₁ and PRF measurements. Data from ex vivo high-intensity focused ultrasound (HIFU) ablations demonstrate good agreement between both PRF and T₁ mapping compared to temperature probes.

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