Abstract #0900

Basal ganglia iron deposition as a biomarker of brain tumor severity

Thomas Reith¹, Robert Wujek^1,2, Robin Karr¹, Kevin Koch¹, Mona Al-Gizawiy¹, and Kathleen Schmainda^1,3

¹Radiology, Medical College of Wisconsin, Milwaukee, WI, United States, ²Biomedical Engineering, Medical College of Wisconsin, Milwaukee, WI, United States, ³Biophysics, Medical College of Wisconsin, Milwaukee, WI, United States

This study utilized quantitative susceptibility mapping (QSM) to investigate basal ganglia iron deposition in 27 patients diagnosed with gliomas. Basal ganglia QSM values of patients with glioblastomas were found to be higher than those of patients with tumors of lower grades, suggesting that iron deposition in the basal ganglia may serve as a biomarker of brain tumor severity.

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