Changes in extracellular matrix are seen in cuff tendinopathy, and in particular, alterations in collagen proportion and property are characteristic. Tendon contains an abundance of short T2 components that rapidly decay to background levels. Thus, UTE sequences are better suited for quantitative evaluation of tendon compared with standard clinical MR sequences. In this study, we assess the sensitivity of multiple UTE biomarkers for the evaluation of rotator cuff degeneration in a controlled laboratory experiment.
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