Because of therapeutic and prognostic significance, the visualizations and quantifications of vascular remodelings are crucial for ischemic stroke brains. In this work, dual contrast MRI was implemented on tMCAO rats as an ischemic stroke model to visualize whole-brain macro- and micro-vascular remodeling. In additional to R1 based UTE-MRA, which showed macrovascular remodeling, simultaneously acquired VSI, Q and MVD metrics from ΔR2-ΔR2*-MRI showed microvascular remodeling in ischemic reperfused rat brains.
This abstract and the presentation materials are available to members only; a login is required.