Abstract #0773

An efficient reconstruction by combining tilted-CAIPI with eddy-current calibration for high-resolution distortion-free diffusion imaging using DIADEM

Myung-Ho In¹, Zijing Dong^2,3, Kawin Setsompop^2,4, Daehun Kang¹, Uten Yarach¹, Yunhong Shu¹, Joshua D Trzasko¹, John Huston¹, and Matt A Bernstein¹

¹Department of Radiology, Mayo Clinic, Rochester, MN, United States, ²A. A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown, MA, United States, ³Department of Electrical Engineering and Computer Science, MIT, Cambridge, MA, United States, ⁴Harvard-MIT Health Sciences and Technology, MIT, Cambridge, MA, United States

As a variant of multi-shot echo-planar imaging, DIADEM (Distortion-free Imaging: A Double Encoding Method) enables high-resolution distortion-free imaging, but the prolonged scan time can be a major challenge. Recently, a novel parallel imaging approach, termed tilted-CAIPI, was suggested to unfold highly accelerated DIADEM data and to substantially reduce the acquisition time. However, the reconstructed image still suffers from eddy-current-induced geometric distortions in diffusion-weighted data. In this work, it is demonstrated that the DIADEM reconstruction becomes more efficient and practical after combining the tilted-CAIPI with the eddy-current calibration approaches.

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