Free-breathing Volumetric Body Imaging for Combined Qualitative and Quantitative Tissue Assessment using MR Multitasking
Zixin Deng1, Anthony G. Christodoulou1, Nan Wang1, Wensha Yang2, Lixia Wang3, Yi Lao2, Fei Han4, Xiaoming Bi4, Bin Sun5, Stephen J Pandol6, Richard Tuli2, Debiao Li1, and Zhaoyang Fan1
1Biomedical Imaging Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA, United States, 2Department of Radiation Oncology, Cedars-Sinai Medical Center, Los Angeles, CA, United States, 3Radiologic Department, Chaoyang Hospital, Beijing, China, 4Siemens Healthineers, Los Angeles, CA, United States, 5Department of Radiology, Fujian Medical University Union Hospital, Fuzhou, China, 6Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, United States
MR has broad clinical applications in body imaging with excellent soft-tissue contrast and qualitative and emerging quantitative assessments, however, respiratory motion has been a critical constraint on the quality of body MR. The aim of this study is to demonstrate the feasibility of a free-breathing volumetric quantitative body imaging technique based on a recently developed MR Multitasking technique. Respiratory phase-resolved T1-, T2-weighted, and T1-, T2-maps can be acquired simultaneously within a single 10-minute scan. Good image quality and comparable T1, T2 measurements to reference scans or published literature were observed in phantom and human studies.
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