Abstract #0646

Pancreatic T1 Mapping and Extracellular Volume Fraction in Patients with Impaired Glucose Tolerance

Yoshifumi Noda¹, Satoshi Goshima¹, Yusuke Tsuji², Kimihiro Kajta¹, Yuta Akamine³, Tomoyuki Okuaki³, Masatoshi Honda³, Hiroshi Kadohara³, Nobuyuki Kawai¹, Hiroshi Kawada¹, Yukichi Tanahashi¹, and Masayuki Matsuo¹

¹Radiology, Gifu University, Gifu, Japan, ²Radiology, Kyoto Prefectural University of Medicine, Kyoto, Japan, ³Philips Healthcare, Tokyo, Japan

The presence of pancreatic fibrosis is a representative feature of the pancreas in patients with impaired glucose tolerance (IGT). The extracellular volume fraction (ECV) is reported to be associated with cardiac and hepatic fibrosis. In this study, we evaluated the feasibility of the ECV of the pancreas based on T1 mapping for the assessment of HbA1c values. Our results showed that increased ECV of the pancreas was significantly correlated with HbA1c values, so the ECV of the pancreas could serve as a potential imaging biomarker for the assessment of patients with IGT.

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