We investigated the value and feasibility of single-direction diffusion-weighted imaging for the assessment of the fetal corpus callosum in 67 healthy fetuses and 26 fetuses with corpus callosum dysplasia. The results showed that single-direction DWI is significantly superior in optimal visibility and contrast ratio (CR) compared to the conventional HASTE and TrueFISP sequences. This study demonstrated that the application of single-direction DWI is promising in fetal corpus callosum lesions and can be used in routine clinical examination.
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