Laminar resolution, functional magnetic resonance imaging (lfMRI) is a noninvasive technique with the potential to distinguish top-down and bottom-up signal contributions on the basis of depth-dependent interactions with distal regions. Hitherto, lfMRI has not been used to investigate whole-brain distributed networks nor complex cognitive tasks. We show here that lfMRI can reveal whole-brain directed networks during word reading. We identify language critical regions based on their association with the top-down signal stream and herewith establish lfMRI for the non-invasive assessment of directed connectivity.
This abstract and the presentation materials are available to members only; a login is required.