Abstract #0568

Development of 1H/13C RF Head Coil for Hyperpolarized 13C Imaging of Human Brain

Junjie Ma¹, Ralph S. Hashoian², Chenhao Sun³, Steve M. Wright³, Alexander Ivanishev⁴, Robert E. Lenkinski⁴, Craig R. Malloy^1,5, Albert P. Chen⁶, and Jae Mo Park^1,4,7

¹Advanced Imaging Research Center, UT Southwestern Medical Center, Dallas, TX, United States, ²Clinical MR Solutions, Brookfield, WI, United States, ³Electrical and Computer Engineering, Texas A&M University, College Station, TX, United States, ⁴Department of Radiology, UT Southwestern Medical Center, Dallas, TX, United States, ⁵Internal Medicine, UT Southwestern Medical Center, Dallas, TX, United States, ⁶GE Healthcare, Toronto, ON, Canada, ⁷Electrical Engineering, UT Dallas, Richardson, TX, United States

A customized ¹H/¹³C RF head coil that consists of a ¹H quadrature transmit (Tx) and receive (Rx) coil and ¹³C quadrature transmit and array receive (QTAR) coils was developed. The performance of the new head coil was evaluated using phantoms and compared to the existing ¹³C-only quadrature Tx/Rx (QTR) head coil. Metabolic imaging of human brain was performed using the ¹H/¹³C head coil, following an injection of hyperpolarized [1-¹³C]pyruvate.

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