Evaluation of Prostate Cancer Detection using Modified MR Dispersion Imaging

A modified version of MR dispersion imaging, mMRDI, is introduced to achieve an effective estimation of intravascular dispersion parameter while maintaining low computational complexity. A total of 53 patients who underwent 3T mp-MRI exams prior to robotic assisted radical prostatectomy are included for evaluation. The estimation of the additional intravascular dispersion related parameter offers minimum model fitting errors and improved delineation between clinically significant prostate cancer and normal tissue assessed by the receiver operating curve analysis (AUC = 0.92).