Single-shot diffusion-weighted imaging is predominantly performed with echo planar imaging today. Spiral imaging allows shorter echo times and thus promises higher signal-to-noise ratio, but is sensitive to various system imperfections. While previous work resorted to using a field camera for this reason, this work demonstrates the feasibility of single-shot diffusion-weighted spiral imaging in the brain on a clinical scanner without extra hardware for field monitoring. Good image quality was generally achieved in volunteers for different diffusion gradient directions up to high b-values using the demand trajectory for gridding, parallel imaging for acceleration, and static main field inhomogeneity mapping for deblurring.
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