Abstract #0219

Dynamic Multi-Coil Technique (DYNAMITE) MRI on Human Brain

Christoph Juchem¹, Michael Mullen², Chathura Kumaragamage³, Lance DelaBarre², Gregor Adriany², Peter B Brown³, Scott McIntyre³, Terence W Nixon³, Michael Garwood², and Robin A de Graaf³

¹Departments of Biomedical Engineering and Radiology, Columbia University, New York, NY, United States, ²Department of Radiology, Center for Magnetic Resonance Research (CMRR), University of Minnesota, Minneapolis, MN, United States, ³Department of Radiology and Biomedical Imaging, Magnetic Resonance Resesarch Center (MRRC), Yale University, New Haven, CT, United States

To date, spatial encoding for human MRI is based on linear X, Y and Z field gradients generated by dedicated X, Y and Z gradient coils. We recently introduced the Dynamic Multi-Coil Technique (DYNAMITE) for B₀ magnetic field modeling and demonstrated DYNAMITE MRI in a miniaturized setup. In this study we report the first realization of multi-slice DYNAMITE MRI of the in vivo human brain in which all gradient fields are purely DYNAMITE-based. The obtained image fidelity is comparable to MRI with conventional gradient coils, paving the way for full-fledged human DYNAMITE MRI systems.

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