Abstract #0147

Amide proton transfer (APT) imaging of uterine cervical cancer; prediction of histological findings

Keisuke Ishimatsu¹, Akihiro Nishie¹, Yukihisa Takayama¹, Yoshiki Asayama¹, Yasuhiro Ushijima¹, Daisuke Kakihara¹, Tomohiro Nakayama¹, Koichiro Morita¹, Seiichiro Takao¹, Osamu Togao¹, Yoshihiro Ohishi², Kenzo Sonoda³, Jochen Keupp⁴, and Hiroshi Honda¹

¹Department of Clinical Radiology, Kyushu university, Fukuoka, Japan, ²Department of Anatomic Pathology, Kyushu university, Fukuoka, Japan, ³Department of Obstetrics and Gynecology, Kyushu university, Fukuoka, Japan, ⁴Philips Research, Hamburg, Germany

It is important to diagnose histological type and existence of parametrial invasion in uterine cervical cancer as correctly as possible because these factors are important in choosing treatment strategies or predicting prognosis. The objective of our study is to investigate whether amide proton transfer (APT) imaging is useful for evaluation of uterine cervical cancer. We compared the APT signal of uterine cervical cancer with different histological findings (histological type and existence of parametrial invasion) using three different durations of presaturation pulse.

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