Abstract #0139

Pilot study on facioscapulohumeral muscular dystrophy patients with dynamic phase contrast imaging of electrically stimulated quadriceps muscles

Xeni Deligianni^1,2, Francesco Santini^1,2, Giorgio Tasca³, Mauro Monforte³, Francesca Solazzo⁴, Raimondo Vitale⁵, Paolo Felisaz⁶, Giancarlo Germani⁴, Niels Bergsland⁴, Enzo Ricci³, and Anna Pichiecchio⁴

¹Department of Radiology/Division of Radiological Physics, University Hospital Basel, Basel, Switzerland, ²Department of Biomedical Engineering, University of Basel, Basel, Switzerland, ³Unità Operativa Complessa di Neurologia, Dipartimento di Scienze dell’Invecchiamento, Neurologiche, Ortopediche e della Testa-Collo, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy, ⁴Neuroradiology Department, IRCCS Mondino Foundation, Pavia, Italy, ⁵University of Pavia, Pavia, Switzerland, ⁶Radiology Department, Desio Hospital ASST, Monza, Italy

Facioscapulohumeral muscular dystrophy is characterized by a peculiar non-linear muscle-by-muscle involvement and is very hard to predict. The purpose of this study was to use dynamic phase contrast MR imaging of electrically stimulated quadriceps muscle to characterize the elastic potential of the muscle in FSHD patients and contribute to the understanding of this challenging disease. Velocity, strain, and strain rate were analyzed and compared to the results of physical examination.

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