This work reports the use of new non-Cartesian k-space trajectories whose improved efficiency allows to significantly reduce MR scan time with minimum deterioration of image quality. Instead of using simple geometrical patterns, we introduce an approach inspired from stippling techniques, which automatically designs optimized sampling patterns along any desired density by taking full advantage of the hardware capabilities. We use our strategy to accelerate the acquisition time of T2*-weighted scans acquired at 7T on in vivo human brains. We compare our method to standard non-Cartesian trajectories (spiral, radial) and demonstrate its superiority regarding image quality and robustness to system imperfections.
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