Accurate quantification of CBF in GM and WM is challenging due to intrinsically low SNR and low spatial resolution of CBF maps. In this study we propose a new approach in quantifying CBF in GM and WM, based on spectral localization by imaging (SLIM), which provides accurate CBF values in compartments with complex shapes, e.g., GM and WM by incorporating high-resolution anatomical information into CBF reconstruction at reduced scan time.
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