Age-related weakness and strength has been shown to have an anatomical basis, with stability of the knee being particularly prone to effects of ageing. Magnetic Resonance Elastography (MRE) was used to obtain muscle size and stiffness measurements in a ‘Younger’ and ‘Older’ group of participants. It was found that the Quadriceps muscle group were primarily impacted by age related atrophy, whilst also increasing in stiffness with age. Furthermore, the muscles along the medial side of the leg showed significantly lower muscle stiffness in ‘Older’ participants which we determined to be a biomarker for age-related anatomical instability.
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