MR Elastography is valuable in evaluating biomechanical stiffness of tissues, which can exhibit marked changes in case of disease. However, the number of cardiac MRE studies remains limited due to challenges in measuring the dynamic muscle tissue using existing MRE sequences and hardware. Here, we aimed to acquire reliable cardiac MRE data by combining a gravitational transducer driven by a novel synchronising strategy with a single-shot SE-EPI-MRE sequence with flow and acceleration compensated motion encoding gradients to image the myocardium in different cardiac phases. Our method reveals higher myocardial stiffness, agreeing with results from biomechanical models/simulations, conflicting with current literature.
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