Previous studies have shown that blood flow in the human retina can be measured using MRI. These studies used single-slice 2D pseudo-continuous arterial spin labeling (pCASL) which has limited spatial coverage and resolution, and is susceptible to through-plane eye motion. In this study, a pCASL with zoom-3D TSE VFA acquisition was developed to provide whole-eye coverage with 0.5×0.5×4mm3 resolution and reduced motion induced image blur. This approach should prove useful for studying different retinal disorders such as glaucoma, diabetic retinopathy and retinal ischemia.
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