Abstract #5459

Inter-site MRI scanner resolution and stability variance revealed by EPI fMRI phantom scans: a multi-site Canadian study

M. Aras Kayvanrad¹, Aditi Chemparathy¹, Stephen Arnott¹, Fan Dong¹, Mojdeh Zamyadi¹, Tom Gee¹, Robert Bartha^2,3, Christopher Scott⁴, Sandra Black⁴, Sean Symons⁴, Glenda MacQueen⁵, Jacqueline Harris⁵, Andrew Davis⁶, Geoffrey Hall⁶, Stefanie Hassel^5,7, and Stephen Strother^1,8

¹Rotman Research Institute, University of Toronto, Toronto, ON, Canada, ²Robarts Research Institute, Western University, London, ON, Canada, ³Medical Biophysics, Western University, London, ON, Canada, ⁴Sunnybrook Research Institute, Toronto, ON, Canada, ⁵The Mathis Centre for Mental Health Research and Education, University of Calgary, Calgary, AB, Canada, ⁶Department of Psychology, Behaviour and Neuroscience, McMaster University, Hamilton, ON, Canada, ⁷School of Life and Health Sciences, Aston University, Birmingham, United Kingdom, ⁸Medical Biophysics, University of Toronto, Toronto, ON, Canada

The Ontario Neurodegenerative Disease Research Initiative (ONDRI) and the Canadian Biomarker Integration Network in Depression (CAN-BIND) are multisite longitudinal studies that employ 12 MRI scanners across Canada (6 in CAN-BIND) to collect neuroimaging data. To ensure comparability of neuroimaging data collected at different sites, fBIRN (functional Biomedical Informatics Research Network) phantoms have been scanned approximately monthly at each site for more than two years to obtain quality assurance (QA) measures from the fBIRN pipeline. In this abstract we present our investigations into within- and between-site variations due primarily to differences in full-width-at-half-maximum (FWHM) measures of imaging resolution.

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